Pituitary gland and growth hormone

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The Diabetogenic Hormone of the Pituitary Gland

NUMEROUS clinical observations have provided indirect evidence that the pituitary gland exercises a significant effect on carbohydrate metabolism. Glycosuria is frequently a part of the acromegalic syndrome (Borchardt, 1908; Goetsch, Cushing and Jacobson, 1911). Houssay (1931) and Eidelsberg (1932) have emphasised that cases of acromegaly often manifest the symptoms and signs of diabetes. The p...

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Pituitary gland: neuropeptides, neurotransmitters and growth factors.

The hypothalamus receives neuronal afferents from numerous sources including inputs from limbic structures, such as the amygdala and hippocampus, and from brainstem regions involved in the regulation of the cardiovascular system and other autonomic functions. These afferents using a vast array of neurotransmitters and neuropeptides influence the activity of the hypothalamic neurons which synthe...

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Growth hormone and prolactin immunoreactivity in the pituitary gland of postnatal little (lit) mice.

Homozygous little (lit/lit) mutant mice exhibit a growth lag which is manifested at approximately two weeks postnatally. Functional aspects of the development of pituitary growth hormone (GH) cells and prolactin (PRL) cells were thus analyzed by means of colloidal gold immunocytochemistry at the ultrastructural level in lit/lit mice and their normal counterparts ranging in age from 5 days postn...

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Growth without growth hormone in combined pituitary hormone deficiency caused by pituitary stalk interruption syndrome

Growth hormone (GH) is an essential element for normal growth. However, reports of normal growth without GH have been made in patients who have undergone brain surgery for craniopharyngioma. Normal growth without GH can be explained by hyperinsulinemia, hyperprolactinemia, elevated leptin levels, and GH variants; however, its exact mechanism has not been elucidated yet. We diagnosed a female pa...

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Pituitary growth hormone and growth hormone-releasing hormone receptor genes and associations with mammographic measures and serum growth hormone.

BACKGROUND Mammographic density is a strong risk factor for breast cancer that is heritable and associated with blood levels of growth hormone and insulin-like growth factor-I (IGF-I). We tested single nucleotide polymorphisms (SNP) in pituitary growth hormone (GH1) and growth hormone-releasing hormone receptor (GHRHR) genes for an association with mammographic density, hormones of the growth h...

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ژورنال

عنوان ژورنال: Southern African Journal of Anaesthesia and Analgesia

سال: 2020

ISSN: 2220-1173,2220-1181

DOI: 10.36303/sajaa.2020.26.6.s3.2553